A Guide to 2C-B-FLY: Ann Shulgin’s Favourite Molecule

The classic dose of 10 mg is easy to manage, this molecule at low doses is much more recreational than mushrooms or LSD. However, the more traditional 10 mg dose is much more manageable, I have never seen anyone have a difficult experience, some of my relatives had no other substance experience other than alcohol and cannabis, however it is important to do it under the right circumstances to have a fulfilling experience and not a stressful one. We really shouldn’t underestimate these molecules that can send us very far, it’s up to us to prepare our mindset well before the trip to be able to explore what we want, or rather what we need. It is a very practical molecule for exploring the arts, I found myself writing poetry and lyrics for hours inspired by a single 10mg dose. At high doses you can start to compare it to Mescaline and 2C-E, which are still considered strong molecules. It is therefore important to remember that at reasonable doses the molecule is well suited for recreation.

2C-B-FLY is a psychedelic phenethylamine, and is the dihydrodifuran analog of 2C-B. 2C-B-FLY belongs to a group of phenethylamine derivatives referred to as the FLY compounds, named for their insect-like appearance of two “wing-like” tetrahydrofuran rings fused on the opposite sides of the central benzene ring. 2C-B-FLY is a substituted molecule of the phenethylamine and dihydrobenzofuran chemical classes.

-B: Effects, Dosage, & Safety

When discovering psychedelics, one quickly discovers LSD and mushrooms, but these molecules can be disorienting and frightening even at fairly low doses. Meditation is easy to engage in under the effects of 2C-B-FLY, and as we often hear that psychedelics replace years of therapy, meditating under trip is for me like meditating for a very long time in experiences of epiphanies and deep realization. The higher dose you take, the more intense these effects will be.With that said, it is impossible to accurately describe the experience through human language.The psychedelic also affects each individual differently and no two trips are the same. Reports have characterized its effects profile as possessing features of 2C-B, mescaline and MDA, with a duration of 6–8 hours (or up to 12 hours in larger doses).

Subjective effects

If 2C-B-FLY does have suspected MAO-altering effects, this could indicate that 2C-B-FLY is more likely to induce serotonin syndrome or general monoamine overload (especially at high dosages) than other serotonergic psychedelics. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠. It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. In a 2007 MAPS newsletter interview, Ann Shulgin revealed that 2C-B-FLY as one of her favorite psychedelic substances while also acknowledging the high variability in responses it seemed to display.

Safety checklist

This compound works through the same mechanism of action as most psychedelics. This act automatically makes any analogs of existing scheduled substances illegal until manually removed. In Canada, 2C-B-FLY is considered a Schedule III substance — which refers to substances that can only legally be sold in pharmacies. It also makes it impossible to sleep for several hours after the experience. Higher doses maintain this effect, but the hallucinogenic action overpowered this effect. A psychoactive dose of 2C-B-FLY is roughly 20 mg, while the psychoactive dose of pure mescaline is closer to 200 mg.

Final Thoughts: What’s The Future of 2C-B-FLY?

Even if you’re ordering from a “reputable” vendor, you should always verify the substance you have before you take it. Users should always do an “allergy test” before increasing the dose, which involves taking a very small dose first to see if they have any reaction. There’s an old adage — “the only difference between poison and medicine is the dose.”

Cannabis

It’s a modification of 2C-B, which itself is a derivative of mescaline. Taking notes during the trip can be interesting because the lightning ideas that surprise us in the middle of the trip have the annoying tendency to disappear. The 2C-B-FLY climbs quite nicely, doing yoga and meditation before and during the climb can help to better settle into the plateau which is the bulk of the experience. The effect is boosted but will depend a lot on your strain of cannabis, depending on if you want to dance to the music until you are exhausted looking for euphoria or ecstasy, or on the contrary lie down in your comforter in the dark to melt into the experience. Otherwise I always mixed the cannabis with 2C-B-FLY I was just waiting for the first 3-4 hours of the high and the beginning of the plateau to pass, that I felt I had some stability with going further.

Both compounds share the same phenethylamine base structure but have entirely different functional groups. In terms of dosage, both compounds are comparable — active in the 5 – 20 mg range, with a threshold somewhere around 5 mg. However, despite the similarities, both compounds remain distinct from each other.

How Strong is 2C-B-FLY Compared To Other Psychedelics?

This is the same mechanism of action used by psilocybin, LSD, mescaline, and most other classical psychedelics.
However, the more traditional 10 mg dose is much more manageable, I have never seen anyone have a difficult experience, some of my relatives had no other substance experience other than alcohol and cannabis, however it is important to do it under the right circumstances to have a fulfilling experience and not a stressful one.
Many psychonauts recommend starting with a light dose but this isn’t necessarily the best way to go.If you start at lower doses, your ego will learn how to control the psychedelic states.
If you take the substance orally, stop eating at least 2-3 hours prior.

Many users report the 2C-B-FLY experience to be similar to MDMA or MDA — especially in lower doses. The visual effects of mescaline are stronger, but both compounds have similar benefits in terms of maintaining functional cognition while high. Even subtle changes in the dose with 2C-B can change the experience from euphoric and empathogenic to powerfully psychedelic and dissociative. The effects of this compound are distinct — meaning it is unique and has key differences to all other substances. It isn’t as powerful as LSD, psilocybin, or 2C-B in terms of psychedelic effects but is still a formidable experience in its own right.

Independent research should always be done to ensure that a combination of two or more substances is safe before consumption. The toxicity and long-term health effects of recreational 2C-B-FLY do not seem to have been studied in any scientific context and the exact toxic dose is unknown. There are currently no anecdotal reports which describe the effects of this compound within our experience index. However, the role of these interactions and how they result in the psychedelic experience remains subject to on-going scientific investigation.

This means that when you take psychedelics, there is more potential for growth but the risks are also higher.
These compounds were casually referred to as the “2C-B-GNAT,” and “2C-B-FLEA” compounds, which contain 5 or 6 membered rings at the 2- vs. 5-positions, respectively.
In comparison to 2C-B, this compound presents a significantly more pronounced body high/load, stronger visual effects, more complex geometry and more in-depth internal hallucinations which are comparable to mescaline, 2C-E or MDA at higher doses.
These molecules have the potential to turn you upside down because it gives the possibility to dive in the darkest confines of its mind.

This psychedelic designer drug hasn’t been around for very long, and it can be tough to find reliable information on it. It’s widely considered one of the best psychedelics for enhancing connection and sexual intimacy. As the public interest in psychedelics continues to grow, more obscure psychedelics like 2C-B-FLY are likely to garner more attention in the coming years. All of this is what serves to induce what we know as the psychedelic experience.

I’ve tried microdosing as well, as well as using it in blends and high doses (40mg+). 2C-B-FLY is a molecule derived from 2C-B which itself is a derivative of mescaline. The purpose of TrippyWiki is to help you find the right psychedelics and use them safely and effectively.

Cannabis can be surprising if taken at the wrong time, once only under 10mg, after smoking a large joint at the very beginning of the climb, I found myself in a rather unpleasant state where I had visuals of a snake trying to bite its own tail all the time, lucky it was only 10mg, I probably would have had a lot more trouble with a bigger dose. With only 10 mg of 2C-B-FLY, one balloon of N20 caused me to completely take off, for 5 minutes I was in a state of intense bodyload, all the effects of 2C-B-FLY were tenfold. But it is advised to avoid combinin with other empathogens – (MDMA, 6-APB, MDA, 5-MAPB, 3-MMC), the 2C-B-FLY is suspected to act as an MAOI, and it is thus necessary to avoid any mixture with molecules releasing serotonin. 2C-B-Fly has synergistic effects with multiple chemicals. Indeed, although it gives access to this particular relation between its part of Shadow and oneself, we manage to keep our feet on the ground thanks to a mindset that leaves us in control of what happens, unlike molecules like mushrooms or LSD that can completely overwhelm us. These molecules have the potential to turn you upside down because it gives the possibility to dive in the darkest confines of its mind.

Users experience changes in the perception of vision and sound, mild to moderate introspection, and an expanded sense of empathy and euphoria. The threshold is reported around 5 mg, and the standard psychoactive dose is between 10 and 25 mg. However, none of these other FLY compounds are as popular in the research chemical space as 2C-B-FLY. FLY compounds are aptly named for the insect-like appearance of their chemical structure. 2C-B-FLY contains a 2C-B molecule at its core with two dihydrofuran rings attached to the central benzene ring.

The dose of 2C-B-FLY is around 20 mg, while the dose of bromo-dragonFLY is around 500 micrograms (not even 1 mg). These effects make it especially useful for promoting arousal and enhancing sexual activity. It’s just strong enough that it’s almost guaranteed to induce feelings of positivity, motivation, and increased feelings of love and connection. In terms of potency, 2C-B-FLY is roughly 10 times as 2c-b-fly potent as mescaline.

This compound is milder than other psychedelics in its class but can still induce powerful psychedelic experiences when used at the upper end of the recommended dose range. If you stick to the recommended doses, it’s unlikely for there to be any serious side effects. While many agree this compound is milder than 2C-B, LSD, and psilocybin in terms of the hallucinogenic potential, it’s still a formidable psychedelic in higher doses.